ISDIN Isdinceutics Age Reverse Night Cream 50ml

PALMITOYL TRIPEPTIDE-38 (Matrixyl Synthe'6) · ALTEROMONAS FERMENT EXTRACT · SODIUM HYALURONATE CROSSPOLYMER

ISDIN's premium anti-aging overnight cream — Matrixyl Synthe'6 (Palmitoyl Tripeptide-38), Alteromonas Ferment Extract, crosslinked Sodium Hyaluronate, and Niacinamide — for clinically visible firming, smoothing, and renewal by morning.

The ISDIN Isdinceutics Age Reverse Night Cream is built on one of the most clinically substantiated anti-aging peptides in formulation science: Palmitoyl Tripeptide-38 (commercially known as Matrixyl Synthe'6), a synthetic mimetic peptide that simultaneously stimulates six key components of the extracellular matrix — Collagen I, III, and IV; Fibronectin; Hyaluronic acid; and Laminin 5 — making it one of the few single ingredients that addresses the full spectrum of dermal structural decline. The cream's texture is richly emollient but not heavy, built on Isodecyl Neopentanoate and a blend of premium esters that absorb without greasy residue, making it appropriate as the only overnight moisturiser rather than an add-on to a separate cream.

Alteromonas Ferment Extract is derived from a deep-sea bacterium that produces extraordinary cold-shock proteins and adaptive enzymes under extreme pressure conditions — these compounds translate in formulation to keratinocyte renewal stimulation and cellular stress resistance. Carnosine (a dipeptide of Alanine and Histidine) provides potent antioxidant activity, specifically targeting protein glycation — the sugar-bonding of skin proteins that contributes to loss of firmness and yellowing. Niacinamide brightens and supports barrier function. Sodium Hyaluronate Crosspolymer (crosslinked, larger molecular weight) sits at the dermis-epidermis junction for sustained, deep hydration rather than surface-only humectancy. This is a night cream for skin that wants serious anti-aging results without the textural compromise of richer formulas.

Rs.30,999.00Rs.27,899.1050ml
  • Matrixyl Synthe'6 (Palmitoyl Tripeptide-38) stimulates 6 extracellular matrix proteins for complete structural renewal - Alteromonas Ferment Extract from deep-sea bacteria stimulates cellular renewal and stress resistance - Niacinamide brightens and supports skin barrier through the night - Crosslinked sodium hyaluronate provides sustained deep hydration with visible plumping by morning
Benefits
PALMITOYL TRIPEPTIDE-38 (Matrixyl Synthe'6) is a palmitoylated tripeptide that activates FIBROBLAST synthesis of six EXTRACELLULAR MATRIX (ECM) components: COLLAGEN I (structural tensile strength), COLLAGEN III (elasticity and wound repair), COLLAGEN IV (basement membrane integrity), FIBRONECTIN (cell adhesion and matrix organisation), HYALURONIC ACID (volumisation), and LAMININ-5 (adhesion junction strengthening). This multi-target ECM stimulation addresses DERMAL ATROPHY comprehensively — clinical studies show 25%+ improvement in fine line and wrinkle reduction versus placebo. ALTEROMONAS FERMENT EXTRACT contains HEAT SHOCK PROTEINS (HSPs) and extremophile COLD SHOCK PROTEINS that activate KERATINOCYTE HSP70 expression, improving cellular stress resistance and renewal signalling. CARNOSINE is a GLYCATION INHIBITOR — it competes with protein lysine residues for reaction with reducing sugars, preventing ADVANCED GLYCATION END-PRODUCTS (AGEs) that cross-link collagen fibres and cause the yellowing and rigidity characteristic of intrinsically aged skin.
Ingredients
Aqua (Water), Butylene Glycol, Isodecyl Neopentanoate, Propanediol, Niacinamide, Glycerin, Betaine, Caprylic/Capric Triglyceride, Silica, Dimethicone, Hydrogenated Polyisobutene, Stearyl Alcohol, Octyldodecanol, Dipentaerythrityl Hexacaprylate/Hexacaprate, Tridecyl Trimellitate, Phenylpropanol, Ammonium Acryloyldimethyltaurate/VP Copolymer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylyl Glycol, Parfum (Fragrance), Cetearyl Alcohol, Potassium Olivoyl Hydrolyzed Oat Protein, Glyceryl Stearate, Carnosine, Tridecyl Stearate, Neopentyl Glycol Dicaprylate/Dicaprate, Glyceryl Oleate, Pentylene Glycol, Sodium Hyaluronate Crosspolymer, Disodium EDTA, PEG-8, Alteromonas Ferment Extract, Hydroxypropyl Cyclodextrin, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Tocopherol, Benzyl Alcohol, Potassium Sorbate, Sodium Benzoate, Ascorbyl Palmitate, Magnesium Chloride, Alcohol Denat, Ascorbic Acid, Citric Acid, Palmitoyl Tripeptide-38, Ci 15985 (Yellow 6), Ci 19140 (Yellow 5)
How to use
After cleansing and applying any serums, smooth a generous amount over face and neck as the final step of your evening routine. Gently press into skin rather than rubbing to maximise peptide absorption. Use nightly. For enhanced results, pair with ISDIN Isdinceutics Retinal Intense Serum applied before this cream — apply the biphasic serum first, allow to absorb, then layer the cream. Allow to work overnight; no rinsing required.
The Edit Promise

Shop With Confidence

Easy Returns 7 Day Return & Exchange Policy
100% Authentic Genuine Products, Sourced & Sealed
Nationwide Delivery 14-21 Business Days
Disclaimer

We import all products directly from authorized distributors. Packaging, batch codes, and shade or formula names may vary slightly from the images shown as brands update their designs from time to time — this never affects the authenticity or quality of what you receive. Every item is 100% genuine and sealed unless listed otherwise.

Complete your regimen

ISDIN K-Ox Eyes Cream 15ml

ISDIN K-Ox Eyes Cream 15ml

The K-Ox Eyes Cream targets the under-eye area with a mechanism most eye creams simply do...

Rs.35,699.00

}
Customer reviews

Loved by skin like yours.

No reviews yet — be the first to share your experience.