ISDIN Fotoultra 100 Active Unify Fusion Fluid SPF50+ 50ml

Name: ISDIN Fotoultra 100 Active Unify Fusion Fluid SPF50+ 50ml
Brand: THE EDIT
Price: 19499.00 PKR
Availability: InStock

TETRAPEPTIDE-30 · PHENYLETHYL RESORCINOL · NIACINAMIDE

SPF50+ that actively treats hyperpigmentation while you wear it — Niacinamide, Phenylethyl Resorcinol, and Tetrapeptide-30 address all three phases of melanogenesis, unified with a photostable broadspectrum UV filter system.

The ISDIN Fotoultra 100 Active Unify addresses one of skincare's most common dual concerns: how to both protect against further sun-triggered pigmentation and actively treat the existing dark spots and uneven tone that UV exposure has already caused. Rather than treating these as separate steps — sunscreen in the morning, brightening serum layered underneath — Active Unify integrates a multi-pathway depigmenting system directly into the SPF50+ formula. Tetrapeptide-30 is a signal peptide that regulates melanogenesis at the genetic level, modulating the expression of key melanogenesis enzymes; Niacinamide (at a meaningful level) inhibits melanosome transfer from melanocytes to keratinocytes — the step that actually creates visible pigmentation in skin; Phenylethyl Resorcinol is a potent tyrosinase inhibitor that reduces melanin production upstream.

This triple mechanism is delivered in ISDIN's signature Fusion Fluid texture — ultralight, transparent (the color variant adds a skin-matching tint), and completely non-greasy on oily and combination skin types. The UVA protection is particularly strong: the formula meets the "2x UVA" standard with a UVA-PF of 49 against SPF 50+ — critical because UVA is the specific radiation that stimulates melanogenesis through OPSIN-3 receptor activation in melanocytes. Using a lower-UVA SPF while treating hyperpigmentation is actively counterproductive; Active Unify closes that gap. For Pakistani skin tones where post-inflammatory hyperpigmentation and sun-induced uneven tone are among the most common concerns, this is an exceptionally targeted daily product.

Triple depigmenting action: Tetrapeptide-30, Niacinamide, and Phenylethyl Resorcinol treat all phases of melanogenesis - Ultra-high UVA protection (SPF 106 UVA-PF 49) prevents UV-triggered melanogenesis - Fusion Fluid texture — ultralight, non-greasy, suitable for oily and combination skin - Panthenol and Allantoin soothe and condition during daily depigmenting treatment

Benefits

TETRAPEPTIDE-30 (Lys-Pro-Val-Thr) regulates MELANIN BIOSYNTHESIS at the epigenetic level by modulating expression of TYROSINASE-RELATED PROTEIN 1 (TRP-1), TRP-2, and MITF — the master transcription factor governing melanogenesis — without cytotoxic effects on melanocytes. PHENYLETHYL RESORCINOL is a TYROSINASE INHIBITOR with a potency approximately 4x greater than KOJIC ACID in competitive enzyme studies; it inhibits both TYROSINASE and TYROSINASE-RELATED PROTEIN 1, reducing melanin synthesis at its enzymatic origin. NIACINAMIDE (Vitamin B3) at effective concentrations inhibits MELANOSOME TRANSFER between melanocytes and keratinocytes by down-regulating protease-activated receptor-2 (PAR-2) on keratinocyte surfaces — addressing pigmentation at a later stage than tyrosinase inhibitors. The three-pathway approach (synthesis inhibition, transfer inhibition, regulatory suppression) provides more complete depigmenting coverage than single-mechanism whitening agents.

Ingredients

Aqua (Water), Dibutyl Adipate, Cyclopentasiloxane, Octocrylene, Niacinamide, Alcohol Denat, Titanium Dioxide [Nano], Butyl Methoxydibenzoylmethane, Cyclohexasiloxane, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Peg-30 Dipolyhydroxystearate, Glycerin, Nylon-12, Peg-10 Dimethicone, Sodium Chloride, Phenoxyethanol, Silica, Dimethicone, Phenylethyl Resorcinol, Disteardimonium Hectorite, Panthenol, Tocopheryl Acetate, Allantoin, Glyceryl Stearate, Parfum (Fragrance), Aluminum Hydroxide, Disodium Edta, Ethylhexylglycerin, Dimethiconol, Peg-8, Sodium Lauroyl Glutamate, Lysine, Tocopherol, Magnesium Chloride, Tetrapeptide-30, Ascorbyl Palmitate, Ascorbic Acid, Citric Acid, Ci 77891 (Titanium Dioxide), Ci 77492 (Iron Oxides), Ci 77491 (Iron Oxides), Ci 77499 (Iron Oxides)

How to use

Apply to face and neck as the last step of your morning skincare routine. Blend evenly and allow to set. Use every morning without exception — the depigmenting actives require consistent daily application to deliver results, and skipping SPF on any morning undermines the treatment by allowing fresh UV-triggered melanogenesis. For accelerated results, pair with a brightening serum in your evening routine. Suitable for all skin types including sensitive skin.

The Edit Promise

Shop With Confidence

Easy Returns 7 Day Return & Exchange Policy

100% Authentic Genuine Products, Sourced & Sealed

Nationwide Delivery 14-21 Business Days

Disclaimer

We import all products directly from authorized distributors. Packaging, batch codes, and shade or formula names may vary slightly from the images shown as brands update their designs from time to time — this never affects the authenticity or quality of what you receive. Every item is 100% genuine and sealed unless listed otherwise.